Introduction
Troxerutin powder, also known as hydroxyethylrutin, is a semi-synthetic derivative of the naturally occurring flavonoid rutin. It is primarily extracted from Sophora japonica (Japanese pagoda tree) buds, one of the richest botanical sources of rutin in the world.
As a member of the flavonoid family of polyphenolic compounds, troxerutin offers significant biological activity. Modern research continues to highlight the important role of flavonoids in supporting vascular health, modulating inflammatory responses, and contributing to overall wellness. Although not classified as essential nutrients, these bioactive compounds are widely recognized for their potential in promoting cardiovascular health and cellular protection.
At Botanical Essence, we specialize in the scalable production of high-purity troxerutin powder under strict GMP conditions. Our product is widely chosen by pharmaceutical manufacturers, nutraceutical formulators, dietary supplement brands, and international distributors seeking consistent quality and full traceability.
Key Functions and Health Benefits
Vascular Protection and Microcirculation Support
Troxerutin is well recognized for its ability to increase capillary resistance, enhance vascular wall elasticity, and regulate vascular permeability. These properties make it particularly valuable in formulations targeting venous insufficiency, capillary fragility, and chronic venous disorders.
Cardiovascular and Metabolic Support
It helps maintain healthy blood pressure levels and contributes to stroke prevention by strengthening blood vessel integrity. Recent studies have also explored its beneficial effects on metabolic disorders, showing promising results in non-obese models of metabolic syndrome.
Anti-inflammatory and Antioxidant Properties
Troxerutin exhibits notable antioxidant activity and mild anti-inflammatory effects. It is often used to help relieve discomfort associated with swelling, bruising, and minor tissue trauma. Additionally, it demonstrates supportive antibacterial properties in various applications.
Comprehensive Vascular Benefits
By improving microcirculation and protecting endothelial function, troxerutin serves as a premium active ingredient in both pharmaceutical preparations and high-end health supplements.
Main Applications
- Pharmaceutical Raw Material: Widely used in drugs for chronic venous insufficiency, hemorrhoids, and vascular disorders.
- Nutraceutical & Dietary Supplements: Popular ingredient in cardiovascular support formulas, vascular health supplements, and antioxidant blends.
- Functional Health Products: Incorporated into capsules, tablets, and powdered drink mixes targeting circulation and metabolic wellness.
- Cosmetic and Personal Care: Occasionally used in topical formulations for its anti-inflammatory and capillary-protective properties.
Product Specifications
Product Name: Troxerutin Powder
CAS No.: 7085-55-4
Appearance: Yellowish-green crystalline powder, slightly hygroscopic
Solubility: Freely soluble in water, slightly soluble in ethanol, practically insoluble in methylene chloride
Quality Specifications (Typical Analysis)
| Items | Specification | Result |
|---|---|---|
| Identification (IR & HPLC) | Conforms to reference standard | Conforms |
| Assay (UV, dried basis) | 95.0% – 105.0% | 99.26% |
| Trihydroxyethylrutin (HPLC) | ≥80.0% | 83.10% |
| Related Substances | Individual impurities ≤5.0% (one ≤10%) | All conform |
| Loss on Drying | ≤5.0% | 3.50% |
| Sulphated Ash | ≤0.4% | 0.02% |
| pH (1% aqueous solution) | 6.0 – 7.2 | 6.9 |
| Bulk Density | 0.25 – 0.45 g/ml | 0.31 g/ml |
| Heavy Metals | ≤20 ppm | <10 ppm |
| Ethylene Oxide (GC) | ≤1 ppm | <1 ppm |
Microbiological Purity
- Total Plate Count: ≤1,000 cfu/g
- Yeast & Mold: ≤100 cfu/g
- E. coli: Absent
- Pseudomonas aeruginosa: Absent
Production Process and Quality Assurance
Botanical Essence utilizes advanced extraction and semi-synthetic technology starting from high-quality Sophora japonica grown in premium cultivation regions of China. Our controlled hydroxyethylation process ensures consistent trihydroxyethylrutin content with minimal impurities.
Every batch undergoes rigorous testing including HPLC analysis, residual solvent testing, heavy metal screening, and microbiological evaluation. Our manufacturing facilities operate under GMP, ISO 9001, and HACCP standards, providing full traceability from raw material to finished powder.
Stability and Safety
Accelerated and long-term stability studies demonstrate that our troxerutin powder maintains excellent chemical and physical stability under recommended storage conditions. Safety evaluations, including abnormal toxicity tests, confirm a strong safety profile suitable for both oral and topical applications.
Storage and Packaging
Recommended Storage: Keep in a cool, dry place, protected from light and moisture.
Packaging Options: 1kg aluminum foil bag, 5kg, 10kg, 25kg fiber drum, or customized according to customer requirements.
Shelf Life: Minimum 24 months when properly stored.
Why Leading Companies Choose Botanical Essence Troxerutin Powder
- High purity and batch-to-batch consistency
- Competitive pricing with strong supply chain reliability
- Comprehensive technical documentation and regulatory support
- Professional R&D team available for formulation guidance
- Proven track record serving global nutraceutical, pharmaceutical, and cosmetic brands
Whether you are a dietary supplement brand owner, pharmaceutical manufacturer, contract formulator, or international distributor, Botanical Essence delivers the quality, compliance, and technical expertise you need to succeed in competitive markets.
For more information, technical data sheets, or samples, please contact us at [email protected].
Botanical Essence – Your Trusted Partner in Premium Botanical Extracts and Functional Ingredients.









