Introduction
Capsaicin (CAS 404-86-4) is the principal bioactive compound responsible for the pungency of chili peppers. Naturally occurring in plants of the Capsicum genus, it serves as a secondary metabolite that protects the plant against herbivores and certain fungi.
In its pure form, capsaicin is a hydrophobic, colorless to off-white crystalline or waxy solid. It acts as a potent irritant to mammals, producing a characteristic burning sensation through activation of the TRPV1 receptor. Due to its unique physiological effects, high-purity capsaicin has become a valuable raw material across the pharmaceutical, dietary supplement, topical analgesic, and functional food industries.
At Botanical Essence, we specialize in the large-scale production and global supply of premium-grade capsaicin powder, delivering consistent quality and full traceability for international manufacturers, brand owners, and distributors.
Key Functions and Benefits
Our capsaicin powder offers multiple scientifically recognized properties that make it highly sought after in product development:
- Natural Topical Analgesic: Acts as a powerful anti-inflammatory and pain-relieving agent. It is widely used in creams, patches, and liniments for muscle pain, joint discomfort, and neuropathic conditions.
- Metabolic Support: Known for its ability to promote thermogenesis and fat oxidation, making it a popular ingredient in weight management and sports nutrition formulations.
- Gastrointestinal Effects: Research indicates it can modulate gastrointestinal motility, help reduce gastric ulceration, and support digestive health at appropriate doses.
- Neurological Activity: Supports increased serotonin production in the brain and exhibits potential anti-convulsant, anti-epileptic, and neuroprotective properties.
- Dermatological Applications: Stimulates melanin production and is used in hair growth and skin conditioning formulations.
- Immune Modulation: Contributes to overall immune system support through its bioactive mechanisms.
Product Specifications (USP Grade)
Product Name: Capsaicin
CAS Number: 404-86-4
Appearance: White to off-white crystalline powder
Purity (HPLC): 98.19% (meets 99.0–101.0% specification range)
Loss on Drying: 0.08% (≤0.2%)
Residue on Ignition: 0.05% (≤0.1%)
Heavy Metals: <10 ppm
Total Impurities: 0.12% (≤2.0%)
Residual Solvents: Toluene <20 ppm (≤30 ppm), Cyclohexane 0.07% (≤0.2%)
Microbiological Quality:
- Total Plate Count: <100 cfu/g (≤1,000 cfu/g)
- Yeast & Mold: <10 cfu/g (≤100 cfu/g)
- E. coli & Salmonella: Negative
Conclusion: Fully complies with USP40 standard.
All batches undergo rigorous third-party testing for purity, residual solvents, heavy metals, and microbial limits to ensure the highest safety and consistency required by regulated markets.
Production and Quality Control
Botanical Essence maintains strict control over the entire manufacturing process. Our capsaicin is extracted from selected high-quality chili pepper raw materials using advanced purification technologies. The production follows cGMP guidelines with comprehensive quality management systems in place.
We provide full traceability from raw material sourcing to final product. Every batch is accompanied by a detailed Certificate of Analysis (COA), and Stability Data Sheets are available upon request. Our product demonstrates excellent stability under recommended storage conditions.
Solubility and Formulation Guidance
Pure capsaicin is lipophilic and exhibits good solubility in ethanol, methanol, and various oils, while remaining practically insoluble in water. This profile makes it highly compatible with oil-based topical formulations, softgels, lipid delivery systems, and alcohol-based tinctures.
For optimal stability, we recommend storing the powder in airtight, light-resistant containers at room temperature, protected from strong oxidizing agents.
Primary Industry Applications
- Pharmaceuticals: Topical pain relief patches, arthritis creams, diabetic neuropathy treatments
- Nutraceuticals & Dietary Supplements: Weight management capsules, metabolic support formulas
- Cosmetics & Personal Care: Anti-cellulite products, hair growth serums, warming formulations
- Functional Foods & Beverages: Spicy flavor enhancement and thermogenic ingredients
- Veterinary Applications: Controlled pungency products for animal repellents and health supplements
Our high-purity capsaicin is particularly valued by formulation scientists for its consistent potency, low odor profile in purified form, and excellent batch-to-batch reproducibility.
Packaging and Supply
Standard packaging includes 1 kg aluminum foil bags, 5 kg, 10 kg, and 25 kg fiber drums, customizable according to customer requirements. We support both small trial orders and large-scale commercial contracts with competitive lead times and reliable global logistics.
Why Choose Botanical Essence as Your Capsaicin Supplier?
With years of specialized experience in botanical extraction and high-purity active ingredient production, Botanical Essence has built long-term strategic partnerships with leading companies including Abbott, Unilever, Shiseido, and various renowned research institutions.
We combine technical expertise, stringent quality systems, and customer-focused service to deliver capsaicin that meets the most demanding international standards. Whether you require pharmaceutical-grade material, bulk raw material for supplement manufacturing, or custom specifications, our team is ready to support your product development and commercial goals.
Contact us today at [email protected] to request samples, obtain the latest specification sheet, or discuss your specific volume requirements for capsaicin powder.
Discover why forward-thinking manufacturers worldwide trust Botanical Essence as their reliable source for high-purity capsaicin and other premium botanical extracts.
