Botanical Essence offers premium Luteolin 98%, a highly purified natural flavonoid widely recognized in the nutraceutical, pharmaceutical, and functional food industries for its potent anti-inflammatory, antioxidant, and respiratory support properties.
What is Luteolin?
Luteolin is a naturally occurring tetrahydroxyflavone found abundantly across the plant kingdom. It is most concentrated in botanicals such as honeysuckle (Lonicera japonica), wild chrysanthemum, perilla leaf, and Prunella vulgaris, as well as in common vegetables including broccoli, cauliflower, carrots, cabbage, and thyme.
As a bioactive flavonoid, luteolin has been extensively studied for its broad spectrum of pharmacological activities, including anti-inflammatory, anti-allergic, uric acid-lowering, antioxidant, antitumor, antibacterial, and antiviral effects. It is particularly valued for its ability to support respiratory health and modulate inflammatory pathways without the side effects commonly associated with long-term glucocorticoid use.
Key Functions and Benefits
Respiratory Health Support
Clinical and preclinical research highlights luteolin’s ability to inhibit macrophage phosphorylation and suppress NF-κB signaling. This mechanism effectively reduces the production of pro-inflammatory cytokines such as IL-6 and TNF-α. By decreasing airway inflammation, luteolin helps relieve chronic cough, excessive sputum, and wheezing associated with conditions including bronchial asthma, COPD, chronic pharyngitis, and allergic rhinitis.
Antioxidant and Cellular Protection
As a powerful polyphenol and free radical scavenger, luteolin demonstrates significant antioxidant capacity. It helps neutralize oxidative stress and supports cellular integrity, making it a valuable ingredient in anti-aging, immune-modulating, and oncological adjuvant formulations.
Uric Acid Management
Luteolin has shown the ability to inhibit uric acid synthesis and promote its excretion, offering potential benefits for individuals managing hyperuricemia and related metabolic conditions.
Additional Bioactivities
Beyond its anti-inflammatory profile, luteolin exhibits phosphodiesterase (PDE) inhibitory activity and has been researched for its potential to interfere with viral entry mechanisms, including SARS and HIV pre-S protein activity.
Production Process and Quality Assurance
At Botanical Essence, our Luteolin 98% is extracted from carefully selected botanical sources using advanced solvent extraction and purification technologies. The entire manufacturing process is conducted under strict cGMP conditions with full traceability from raw material to finished powder.
Our product features:
- 98%+ purity verified by HPLC
- Light yellow fine powder with characteristic odor and taste
- Excellent batch-to-batch consistency
- Low residual solvents and heavy metals
- Rigorous testing for pesticides, aflatoxins, and microbial limits
Quality Specifications
| Test Item | Specification | Result |
|---|---|---|
| Assay (HPLC) | ≥ 98.0% Luteolin | 99.04% |
| Appearance | Light yellow powder | Complies |
| Particle Size | 100% pass 80 mesh | Complies |
| Loss on Drying | ≤ 5.0% | 2.06% |
| Total Ash | ≤ 2.0% | 0.64% |
| Heavy Metals (Pb, As, Cd, Hg) | Meets USP/EP standards | Compliant |
| Pesticide Residues | ND (USP/EP compliant) | Negative |
| Aflatoxins | ≤ 10 ppb | Negative |
| Total Plate Count | < 1,000 cfu/g | 35 cfu/g |
| Yeast & Mold | < 100 cfu/g | 12 cfu/g |
| E. coli / Salmonella / S. aureus | Negative | Negative |
Analytical Method
Luteolin content is determined using a validated HPLC method with a C18 column, UV detection at 349 nm, and methanol-water mobile phase. The method demonstrates excellent linearity, precision (RSD 1.82%), and recovery (99.13%).
Solubility and Formulation Compatibility
Luteolin is lipophilic and shows good solubility in alkaline aqueous solutions and organic solvents such as DMSO, ethanol, and methanol. It is widely used in dietary supplements, functional beverages, capsules, tablets, and topical formulations. Its stability under proper storage conditions makes it ideal for long-shelf-life products.
Packaging and Storage
- Standard Packaging: 1 kg aluminum foil bag, 25 kg fiber drum
- Storage: Keep in a cool, dry place away from direct sunlight and moisture
- Shelf Life: Minimum 24 months when properly stored
Stability Data Sheet is available upon request.
Why Leading Manufacturers Choose Botanical Essence Luteolin
- High-purity 98%+ standardized extract
- Vertically integrated supply chain with full traceability
- Comprehensive regulatory documentation and testing
- Consistent quality suitable for global markets (US, EU, ASEAN)
- Professional technical support for formulation development
Our Luteolin is trusted by leading companies in the nutraceutical, pharmaceutical, and cosmeceutical industries seeking reliable, science-backed botanical ingredients.
Contact us today at [email protected] to request samples, specifications, or discuss custom purification requirements.
Botanical Essence – Delivering Premium Botanical Extracts with Integrity and Excellence.
