1. Introduction

Dandelion Extract (CAS: 84775-55-3) has long been employed in treating liver and biliary conditions for hundreds of years. During the 10th and 11th centuries, Arab physicians documented its therapeutic applications extensively. By the 16th century in Britain, it earned recognition as an official apothecary remedy under the name herbal dandelion, gaining broad acceptance. It emerged as a favored treatment for liver and gastrointestinal issues. In Germany during the same era, dandelion was commonly applied to purify the blood and alleviate liver blockages. This herb enjoys global recognition, with countries like Switzerland, Poland, Hungary, and Russia continuing to incorporate it into their official pharmacopeias. Numerous investigations into its pharmacological and nutritive properties have been conducted across various European nations. In traditional practices of China, India, and Nepal, dandelion has served as a liver-supporting herb for centuries. It is popularly utilized as a revitalizing agent in North America and Eastern Europe. The FDA has authorized dandelion extract as a GRAS (Generally Recognized as Safe) food additive. This extract serves as a flavoring component in diverse consumable items, such as alcoholic drinks (like bitters and wines), non-alcoholic beverages, ice creams, confectionery, pastries, gels, custards, and dairy products.

2. Flow Chart

Dandelion powder+ water

↓

Mix and adjust pH

↓

Hydrolysis

↓

Separate

↓

Refined

↓

Concentrate

↓

spray drying

↓

Packaging finished products

3. Quality Standard

Dandelion Extract is derived from Taraxacum borealisinese Kitam or related dried aerial parts of the same genus. It possesses a sweet yet mildly bitter flavor, a cooling property, and is non-toxic. Traditionally, it addresses boils, abscesses, mastitis, pharyngitis, damp-heat induced jaundice, and urinary discomfort from heat. Dandelion is also a source of proteins, lipids, and saccharides, offering substantial nutritional benefits and qualifying as a dual-purpose food and medicine. It thrives primarily in China's northeastern, eastern, and southwestern regions, with abundant wild supplies in Heilongjiang province.

This study meticulously examines the quality criteria for dandelion extract. Building on established benchmarks, we developed an analytical protocol using HPLC fingerprinting. The fingerprint profile employs methanol-0.1% glacial acetic acid as the elution solvent. Over a 120-minute run, the resulting chromatograms demonstrate consistent elution patterns across five samples, revealing three shared peaks beyond caffeic acid. Validation of this fingerprint method confirms excellent instrument precision, procedural reproducibility, stability, and robustness. These attributes underscore the method's reliability, selectivity, adaptability, ease of use, and consistency, positioning it as an effective tool for quality assurance in dandelion extract.

Extending from the fingerprint analysis, we refined the overall quality specifications. Dandelion extract appears as a listed ingredient on page 148 of Volume 13 in the Ministry of Health's Standards for Traditional Chinese Medicine Formulations. It is referenced in the quality specs for "Compound Puqin Tablets," but only under the preparation clause, lacking additional assays. Drawing from pharmacopeial reviews and extensive lab work, we established comprehensive quality guidelines for dandelion extract. The primary goal is to enhance internal quality oversight through these upgraded standards.

4. Chromatogram

5. Functions

Dandelion Extract is abundant in compounds like dandelion sterols, choline, inulin, and pectin. Its leaves feature lutein, myricetin, and chlorogenic acid; flowers include kaempferol, lutein, and apigenin; pollen holds β-sitosterol, folic acid, and vitamin C; while green bracts contain chlorogenic acid, and stems yield β-sitosterol and lupeol. Botanical Essence sources Taraxacum officinale, a premium dandelion variant enriched with 5% bioflavonoids, presenting as a light brown powder with excellent aqueous solubility, ideal for formulating supplements and pharmaceuticals in various formats.

Dandelion root extract powder supports relief from liver swelling and blockages. Renowned as a potent detoxifying herb, it purifies toxins and impurities from the bloodstream, gallbladder, liver, and kidneys. It promotes bile production and aids in eliminating excess fluids stemming from liver impairment.

The 1991 issue (Volume 3, Issue 4) of the Australian Journal of Medical Plants references two key studies: one by Vivarelli in 1938 and another conducted in the UK, both validating dandelion's hepatoprotective effects. These trials showed success in managing hepatitis, edema, jaundice, and dyspepsia—conditions linked to disrupted bile flow. It proves beneficial in initial phases of cirrhosis, including alcohol-related cases.

6. Application

Dandelion Extract powder can enhance bile secretion by up to twofold, playing a vital role in toxin removal. Bile flow represents the body's innate mechanism for shuttling liver toxins to the intestines for elimination. Beyond accelerating bile output, dandelion extract rejuvenates biliary performance, as evidenced by research from the UK. This choleretic action is particularly advantageous for hepatic and gallbladder inflammations, gallstone clearance, obstructions, and jaundice.

Dandelion root extract acts as a robust diuretic. In contrast to conventional diuretics that deplete potassium, dandelion preserves it and supplies ample minerals, potentially serving as a natural potassium source.

7. Stability and Safety Study

Extensive evaluations on stability and safety have been performed for this product. Accelerated and extended stability testing indicates robust performance; animal-based clinical assessments confirm its safety profile.

8. Third Party Test Report

Over the years, we've commissioned multiple third-party analyses from reputable labs such as SGS, Eurofins, and Pony. We can accommodate any specific testing needs you require. Below are sample reports for this product as a reference.

9. Certifications

Botanical Essence holds certifications including HALAL, Kosher, ISO22000, HACCP, EU compliance, and USDA Organic, issued by accredited bodies.

10. Patent

Years of dedicated research and development have gone into optimizing this extract, resulting in secured patents for it in China.

11. Main Clients

Botanical Essence is a trusted supplier to leading global manufacturers in the food, pharmaceutical, and cosmetics sectors.

12. Exhibitions

We regularly participate in major events such as CPhI, FIC, Vitafoods, and SupplySide West to broaden our reach worldwide, with the hope that Botanical Essence products bring value to people everywhere.

13. Customers Feedback

With warehouses in Miami, USA, and Italy, EU, plus online platforms on Alibaba, we ensure seamless purchasing experiences that our clients appreciate and endorse.

Elizabeth Morgan